SPANXN5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPANXN5 mutation is significantly associated with the RNA expression of many other genes, with 1,012 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPANXN5-associated genes across cancer lineages are MIR489, RPL23AP7, and RNA5SP428. Each is linked with SPANXN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXN5-to-partner and partner-to-SPANXN5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXN5→partner) and Y-score (partner→SPANXN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMIR489 →+0.733+7.930<.001.00832
SKCMRPL23AP7 →+0.406+3.604.006.00132
BLCARNA5SP428 →+0.213+7.640<.001.00932
UCECSREBF2-AS1 →+0.625+3.470<.001.00232
UCECSPATA12 →+0.403+2.850.003.00132
UCECRNY4P27 →+0.161+3.338<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,012 associations by consensus.

Exploration