Across TCGA cell cohorts, SPANXN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 410 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible SPANXN3-associated GO terms across cancer lineages are Negative regulation of mitochondrial depolarization, Respiratory burst involved in defense response, and Skin development. Each is linked with SPANXN3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPANXN3-to-partner and partner-to-SPANXN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXN3→partner) and Y-score (partner→SPANXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of mitochondrial depolarization →	+0.223	+0.042	<.001	.004	3	3
BLOOD_Leukemia	Respiratory burst involved in defense response →	-0.193	-0.016	.002	.008	3	3
KIDNEY	Skin development →	+0.073	+0.941	.005	.002	3	3
KIDNEY	Negative regulation of viral process →	+0.147	+1.046	.003	.005	3	3
BREAST	Negative regulation of membrane depolarization →	+0.232	+0.042	<.001	.004	3	3
BREAST	Negative regulation of protein localization to cell surface →	+0.086	+0.028	.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

Exploration

SPANXN3 survival (RNA) · tumor vs normal (RNA) · all SPANXN3 data types