SPAG9

Across TCGA patient cohorts, SPAG9 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,052 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPAG9-associated proteins across cancer lineages are MANF, PDIA4, and RAI14. Each is linked with SPAG9 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPAG9-to-partner and partner-to-SPAG9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAG9 versus MANF in LSCC, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG9→partner) and Y-score (partner→SPAG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MANF →	-0.457	-0.316	<.001	<.001	3	6
GBM	PDIA4 →	-0.404	-0.283	<.001	<.001	3	5
OV	RAI14 →	+0.317	+0.691	.002	<.001	3	5
LSCC	ST6GAL1 →	-0.589	-0.326	<.001	<.001	3	5
LUAD	SPAG9_S1188 →	+0.440	+0.374	<.001	<.001	3	5
LSCC	AKAP1 →	+0.411	+0.328	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,052 associations by consensus.

SPAG9 vs MANF — LSCC

Explore this scatter interactively →