SPA17P1

Across TCGA patient cohorts, SPA17P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,086 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPA17P1-associated proteins across cancer lineages are TOP2A_S1247, CASC3_S373, and ECT2_T359. Each is linked with SPA17P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPA17P1-to-partner and partner-to-SPA17P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPA17P1 versus TOP2A_S1247 in UCEC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPA17P1→partner) and Y-score (partner→SPA17P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOP2A_S1247 →	-0.689	-0.566	.001	.001	3	4
LUAD	CASC3_S373 →	-0.521	-0.534	.001	.007	3	4
LUAD	ECT2_T359 →	-0.708	-0.371	.003	.001	3	4
UCEC	PDCD4_S457 →	+0.363	+0.583	.006	.002	3	4
UCEC	RFC1_T506 →	-0.780	-0.719	<.001	.001	3	3
LSCC	SMC2 →	-0.471	-0.343	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,086 associations by consensus.

SPA17P1 vs TOP2A_S1247 — UCEC

Explore this scatter interactively →