SOX14

Across TCGA cell cohorts, SOX14 RNA expression is significantly associated with the go_rna of many other GO terms, with 118 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOX14-associated GO terms across cancer lineages are Heart formation, Fas signaling pathway, and Leukemia inhibitory factor signaling pathway. Each is linked with SOX14 in more than 2 cancer types. Because this analysis shows association rather than direction, both SOX14-to-partner and partner-to-SOX14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heart formation grouped by SOX14-low versus SOX14-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX14→partner) and Y-score (partner→SOX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Heart formation →	+0.191	+0.804	<.001	.005	3	3
LARGE_INTESTINE	Fas signaling pathway →	-0.101	-0.619	<.001	.007	3	2
LARGE_INTESTINE	Leukemia inhibitory factor signaling pathway →	-0.100	-0.825	.004	.002	3	2
LARGE_INTESTINE	Nuclear protein quality control by the ubiquitin-proteasome system →	+0.110	+0.722	<.001	.005	3	2
LARGE_INTESTINE	Cell surface receptor signaling pathway via STAT →	-0.039	-0.818	.001	.003	3	2
BLOOD_Leukemia	Regulation of microglial cell migration →	-0.658	-0.001	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 118 associations by consensus.

Heart formation by SOX14 expression — LARGE_INTESTINE

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