SOCS7

Across TCGA patient cohorts, SOCS7 protein abundance is significantly associated with the RNA expression of many other genes, with 244 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SOCS7-associated genes across cancer lineages are SULT2A1, WFDC3, and VPS26C. Each is linked with SOCS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOCS7-to-partner and partner-to-SOCS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOCS7 versus SULT2A1 in GBM, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS7→partner) and Y-score (partner→SOCS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SULT2A1 →	+0.056	+1.031	<.001	.008	3	1
GBM	WFDC3 →	+0.354	+0.831	.009	.005	3	1
GBM	VPS26C →	+0.378	+1.081	.002	.005	3	1
GBM	ANKRD61 →	+0.693	+1.113	.009	.003	3	1
GBM	TRANK1 →	+0.992	+1.116	.003	.008	3	1
GBM	LINC00917 →	+0.020	+0.946	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 244 associations by consensus.

SOCS7 vs SULT2A1 — GBM

Explore this scatter interactively →