SOAT1

Across TCGA cell cohorts, SOAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,609 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SOAT1-associated GO terms across cancer lineages are Low-density lipoprotein particle clearance, Macrophage derived foam cell differentiation, and Regulation of early endosome to late endosome transport. Each is linked with SOAT1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SOAT1-to-partner and partner-to-SOAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Low-density lipoprotein particle clearance grouped by SOAT1-low versus SOAT1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOAT1→partner) and Y-score (partner→SOAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Low-density lipoprotein particle clearance →	+0.239	+1.382	<.001	<.001	3	15
BREAST	Macrophage derived foam cell differentiation →	+1.205	+1.872	<.001	<.001	3	15
BREAST	Regulation of early endosome to late endosome transport →	+0.105	+1.128	<.001	<.001	3	13
STOMACH	Foam cell differentiation →	+0.317	+2.127	<.001	<.001	3	13
BONE	Regulation of hippo signaling →	+0.090	+1.216	<.001	.001	3	13
SOFT_TISSUE	Positive regulation of translational initiation →	+0.108	+1.069	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,609 associations by consensus.

Low-density lipoprotein particle clearance by SOAT1 expression — KIDNEY

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