SNX9

Across TCGA patient cohorts, SNX9 mutation is significantly associated with the RNA expression of many other genes, with 1,966 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX9-associated genes across cancer lineages are LSM10, TANGO2, and H2BC13. Each is linked with SNX9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX9-to-partner and partner-to-SNX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM10 grouped by SNX9-low versus SNX9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX9→partner) and Y-score (partner→SNX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM10 →	+0.494	+2.807	<.001	<.001	3	2
UCEC	TANGO2 →	+0.507	+2.332	<.001	<.001	3	2
UCEC	H2BC13 →	+0.707	+2.818	<.001	<.001	3	2
UCEC	CCDC137 →	+0.391	+2.157	.003	.009	3	2
UCEC	UBE2L3 →	+0.302	+2.330	.003	.003	3	2
UCEC	BCAM →	-0.947	-3.584	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,966 associations by consensus.

LSM10 by SNX9 expression — UCEC

Explore this box plot interactively →