SNX9

Across TCGA pan-cancer cohorts, SNX9 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SNX9’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SNX9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNX9 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

LUAD, KICH, and BLCA are the cancer types where SNX9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNX9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+1.258	<.001	9	view →
KICH	Female	II,III,IV	−1.241	<.001	9	view →
BLCA	All	All	−0.622	.006	7	view →
UCEC	All	All	−0.839	<.001	6	view →
LUSC	Male	All	+0.430	<.001	5	view →
COAD	All	All	−0.316	<.001	4	view →
READ	All	All	−1.053	.001	3	view →
CHOL	All	II,III,IV	+0.900	.012	3	view →
PRAD	All	All	−0.224	.009	2	view →
BRCA	All	All	−0.139	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SNX9–LUAD

Open the LUAD breakdown →