SNX6

Across TCGA patient cohorts, SNX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,198 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SNX6-associated proteins across cancer lineages are STRN3, FKBP3, and ARHGAP5. Each is linked with SNX6 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX6-to-partner and partner-to-SNX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX6 versus STRN3 in LUAD, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX6→partner) and Y-score (partner→SNX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	STRN3 →	+0.339	+0.657	<.001	<.001	3	6
HNSC	FKBP3 →	+0.378	+0.611	<.001	<.001	3	6
HNSC	ARHGAP5 →	+0.325	+0.846	<.001	<.001	3	6
LSCC	SNX5 →	-0.300	-0.479	<.001	.001	3	5
LSCC	GNPNAT1 →	+0.429	+0.491	<.001	<.001	3	5
COAD	BCKDHB →	-0.357	-0.585	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,198 associations by consensus.

SNX6 vs STRN3 — LUAD

Explore this scatter interactively →