SNX6

Across TCGA patient cohorts, SNX6 protein abundance is significantly associated with the RNA expression of many other genes, with 16,611 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNX6-associated genes across cancer lineages are FLI1, GIMAP1, and ATP8B4. Each is linked with SNX6 in more than 8 cancer types. Because this analysis shows association rather than direction, both SNX6-to-partner and partner-to-SNX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX6 versus FLI1 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX6→partner) and Y-score (partner→SNX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FLI1 →	+0.706	+0.214	<.001	<.001	3	9
GBM	GIMAP1 →	+0.725	+0.297	<.001	<.001	3	9
HNSC	ATP8B4 →	+0.807	+0.221	<.001	<.001	3	8
LSCC	STARD8 →	+0.735	+0.214	<.001	<.001	3	8
UCEC	GIMAP6 →	+0.816	+0.165	.002	.001	3	8
GBM	TLR7 →	+0.988	+0.238	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,611 associations by consensus.

SNX6 vs FLI1 — HNSC

Explore this scatter interactively →