SNX31

Across TCGA cell cohorts, SNX31 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SNX31-associated genes across cancer lineages are OR11G2, C16orf90, and SLC22A8. Each is linked with SNX31 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX31-to-partner and partner-to-SNX31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11G2 grouped by SNX31-low versus SNX31-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX31→partner) and Y-score (partner→SNX31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR11G2 →	+0.010	+3.930	<.001	.003	3	1
SKIN	C16orf90 →	+0.028	+4.882	<.001	<.001	3	1
BLOOD_Leukemia	SLC22A8 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR6P1 →	+0.016	+5.201	<.001	.006	3	1
CNS	SPAM1 →	+0.006	+5.321	<.001	.005	3	1
CNS	C10orf71 →	+0.016	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR11G2 by SNX31 expression — SKIN

Explore this box plot interactively →