SNX29

Across TCGA cell cohorts, SNX29 mutation is significantly associated with the RNA expression of many other genes, with 192 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX29-associated genes across cancer lineages are OR2D3, GPR26, and PTCRA. Each is linked with SNX29 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX29-to-partner and partner-to-SNX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by SNX29-low versus SNX29-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX29→partner) and Y-score (partner→SNX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR2D3 →	+0.018	+3.432	<.001	.008	3	2
OESOPHAGUS	GPR26 →	+0.036	+4.906	<.001	.006	3	1
OESOPHAGUS	PTCRA →	+0.413	+4.906	<.001	.006	3	1
OESOPHAGUS	C10orf71 →	+0.006	+4.906	<.001	.006	3	1
BLOOD_Leukemia	APOL5 →	+0.018	+3.475	<.001	.006	3	1
BLOOD_Leukemia	INSM2 →	+0.176	+4.091	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

OR2D3 by SNX29 expression — STOMACH

Explore this box plot interactively →