SNX29

Across TCGA pan-cancer cohorts, SNX29 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SNX29’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where SNX29 RNA is repressed in tumor relative to normal tissue. In most cancer types SNX29 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, LIHC, and KICH are the cancer types where SNX29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNX29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.867	<.001	9	view →
LIHC	Female	II,III,IV	+0.974	<.001	8	view →
KICH	Male	All	−1.002	<.001	7	view →
HNSC	Female	III,IV	+0.911	.002	7	view →
LUSC	All	II,III,IV	−0.467	.004	4	view →
COAD	All	II,III,IV	−0.305	.010	4	view →
BRCA	All	All	−0.277	<.001	4	view →
CHOL	All	All	+2.135	<.001	3	view →
UCEC	All	All	−0.843	<.001	2	view →
READ	Female	All	−0.811	.049	1	view →
LUAD	All	All	−0.206	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SNX29–THCA

Open the THCA breakdown →