SNX16

Across TCGA patient cohorts, SNX16 mutation is significantly associated with the RNA expression of many other genes, with 1,637 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX16-associated genes across cancer lineages are RN7SL248P, TRIM48, and SMSP1. Each is linked with SNX16 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX16-to-partner and partner-to-SNX16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by SNX16-low versus SNX16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX16→partner) and Y-score (partner→SNX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.059	+3.137	<.001	.005	3	2
COAD	TRIM48 →	+0.145	+5.392	<.001	.002	3	2
COAD	SMSP1 →	+0.215	+4.646	<.001	.004	3	2
CESC	LINC02559 →	+0.604	+6.342	.001	.001	3	2
UCEC	DUTP5 →	+0.144	+2.064	<.001	.002	3	2
BLCA	TOMM22P1 →	+0.129	+4.685	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,637 associations by consensus.

RN7SL248P by SNX16 expression — UCEC

Explore this box plot interactively →