SNX15

Across TCGA patient cohorts, SNX15 mutation is significantly associated with the RNA expression of many other genes, with 2,428 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX15-associated genes across cancer lineages are RN7SL271P, FABP5P10, and RPL35AP19. Each is linked with SNX15 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX15-to-partner and partner-to-SNX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL271P grouped by SNX15-low versus SNX15-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX15→partner) and Y-score (partner→SNX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL271P →	+0.091	+5.365	<.001	.002	3	3
COAD	FABP5P10 →	+0.193	+3.455	.003	<.001	3	3
BRCA	RPL35AP19 →	+0.141	+4.331	.006	.003	3	2
UCEC	RNA5SP414 →	+0.691	+2.255	<.001	.009	3	2
UCEC	GEMIN4 →	+0.800	+3.807	<.001	<.001	3	2
UCEC	CYB5D1 →	+0.383	+3.370	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,428 associations by consensus.

RN7SL271P by SNX15 expression — BRCA

Explore this box plot interactively →