SNX15

Across TCGA pan-cancer cohorts, SNX15 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SNX15’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where SNX15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNX15 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

LIHC, BRCA, and THCA are the cancer types where SNX15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNX15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.199	<.001	8	view →
BRCA	Female	All	−0.263	<.001	6	view →
THCA	Female	All	−0.164	.001	6	view →
HNSC	Female	All	+0.157	.010	5	view →
UCEC	All	All	−0.182	.005	4	view →
CHOL	All	All	+0.475	<.001	3	view →
BLCA	All	All	+0.175	.048	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SNX15–LIHC

Open the LIHC breakdown →