SNX15

Across TCGA cell cohorts, SNX15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,222 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX15-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Positive regulation of supramolecular fiber organization, and Positive regulation of attachment of mitotic spindle microtubules to kinetochore. Each is linked with SNX15 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNX15-to-partner and partner-to-SNX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by SNX15-low versus SNX15-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX15→partner) and Y-score (partner→SNX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cytoskeleton organization →	+0.055	+0.860	<.001	<.001	3	11
OVARY	Positive regulation of supramolecular fiber organization →	+0.064	+0.747	<.001	<.001	3	11
BREAST	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.208	+1.006	<.001	<.001	3	10
URINARY_TRACT	Regulation of metaphase plate congression →	+0.159	+1.086	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of gluconeogenesis →	+0.107	+0.634	.001	.004	3	9
BREAST	Negative regulation of chromosome segregation →	+0.082	+0.618	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,222 associations by consensus.

Positive regulation of cytoskeleton organization by SNX15 expression — OVARY

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