SNX13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNX13 mutation is significantly associated with the RNA expression of many other genes, with 4,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX13-associated genes across cancer lineages are RNA5SP198, DUTP5, and RNU6-543P. Each is linked with SNX13 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNX13-to-partner and partner-to-SNX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by SNX13-low versus SNX13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX13→partner) and Y-score (partner→SNX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP198 →+0.224+4.559<.001.00634
LIHCDUTP5 →+0.101+6.676<.001<.00133
PRADRNU6-543P →+0.308+7.939<.001.00833
LUADHMGN1P11 →+0.266+3.303<.001.00433
UCECPACRG →-1.071-3.392<.001<.00133
UCECUQCR11 →+0.351+2.660<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,514 associations by consensus.

RNA5SP198 by SNX13 expression — CESC

Box plot of RNA5SP198 in SNX13-low vs SNX13-high samples in CESC.

Explore this box plot interactively →

Exploration