SNU13

Across TCGA patient cohorts, SNU13 mutation is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNU13-associated genes across cancer lineages are RNU2-58P, RNU6-881P, and RNU6-382P. Each is linked with SNU13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNU13-to-partner and partner-to-SNU13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-58P grouped by SNU13-low versus SNU13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNU13→partner) and Y-score (partner→SNU13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU2-58P →	+0.732	+3.720	<.001	.006	3	2
SKCM	RNU6-881P →	+0.319	+5.797	<.001	.001	3	2
BRCA	RNU6-382P →	+0.358	+8.471	<.001	.005	3	1
BRCA	TSPY22P →	+0.049	+8.471	<.001	.005	3	1
UCEC	INSL6 →	+0.966	+3.786	<.001	.005	3	1
COAD	MIR1288 →	+0.782	+5.435	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

RNU2-58P by SNU13 expression — UCEC

Explore this box plot interactively →