SNTA1

Across TCGA patient cohorts, SNTA1 mutation is significantly associated with the RNA expression of many other genes, with 411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNTA1-associated genes across cancer lineages are RNU6-73P, TXN2, and RN7SKP227. Each is linked with SNTA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNTA1-to-partner and partner-to-SNTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-73P grouped by SNTA1-low versus SNTA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTA1→partner) and Y-score (partner→SNTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-73P →	+0.197	+3.489	.001	.003	3	3
UCEC	TXN2 →	+0.416	+2.556	.004	.009	3	2
CESC	RN7SKP227 →	+0.073	+4.144	<.001	.009	3	2
CESC	TRAJ12 →	+0.632	+3.608	<.001	.004	3	2
BLCA	RNU6-141P →	+0.705	+4.216	<.001	.003	3	2
CESC	SMARCE1P2 →	+0.090	+4.129	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 411 associations by consensus.

RNU6-73P by SNTA1 expression — UCEC

Explore this box plot interactively →