SNTA1

Across TCGA pan-cancer cohorts, SNTA1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SNTA1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SNTA1 RNA is repressed in tumor relative to normal tissue. In most cancer types SNTA1 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, THCA, and KIRC are the cancer types where SNTA1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNTA1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	IV	−2.554	<.001	12	view →
THCA	All	IV	−2.404	<.001	11	view →
KIRC	All	III,IV	+0.741	<.001	11	view →
LIHC	Female	II,III,IV	+1.778	<.001	8	view →
LUAD	All	III,IV	+0.655	<.001	7	view →
BRCA	All	All	−0.774	<.001	6	view →
KICH	All	All	+0.759	<.001	5	view →
LUSC	All	All	+0.362	.002	4	view →
KIRP	All	IV	−0.867	.048	2	view →
CHOL	All	All	+0.591	.027	2	view →
PAAD	Female	All	+0.419	.007	2	view →
STAD	All	III,IV	−1.154	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SNTA1–BLCA

Open the BLCA breakdown →