SNTA1

Across TCGA cell cohorts, SNTA1 mutation is significantly associated with the mutation status of many other genes, with 2,204 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNTA1-associated genes across cancer lineages are KCTD3, WDR7, and ZFP64. Each is linked with SNTA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNTA1-to-partner and partner-to-SNTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCTD3 grouped by SNTA1-low versus SNTA1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNTA1→partner) and Y-score (partner→SNTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KCTD3 →	+4.321	+5.285	.005	.005	1	4
LARGE_INTESTINE	WDR7 →	+2.289	+3.182	.008	.008	1	3
LARGE_INTESTINE	ZFP64 →	+1.693	+3.506	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	DDX20 →	+4.954	+4.392	.008	.008	1	3
LARGE_INTESTINE	KIAA0100 →	+2.321	+4.129	.001	.001	1	3
BLOOD_Leukemia	SENP1 →	+4.736	+5.560	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,204 associations by consensus.

KCTD3 by SNTA1 expression — BLOOD_Leukemia

Explore this box plot interactively →