SNRPN

Across TCGA cell cohorts, SNRPN mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SNRPN-associated genes across cancer lineages are OR1L6, MINAR2, and USP17L4. Each is linked with SNRPN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPN-to-partner and partner-to-SNRPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by SNRPN-low versus SNRPN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPN→partner) and Y-score (partner→SNRPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
SKIN	MINAR2 →	+0.013	+4.977	<.001	.007	3	1
SKIN	USP17L4 →	+0.022	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	FAM71C →	+0.026	+3.672	<.001	.002	3	1
LUNG_NSCLC_LUAD	KHDC3L →	+0.022	+2.951	.001	.003	3	1
LUNG_NSCLC_LUAD	SLC35G4 →	+0.011	+3.681	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR1L6 by SNRPN expression — LARGE_INTESTINE

Explore this box plot interactively →