SNRPG

Across TCGA patient cohorts, SNRPG mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPG-associated genes across cancer lineages are RNU6-1227P, SNRPGP7, and RNU6-719P. Each is linked with SNRPG in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPG-to-partner and partner-to-SNRPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1227P grouped by SNRPG-low versus SNRPG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPG→partner) and Y-score (partner→SNRPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1227P →	+0.229	+4.582	.004	.005	3	2
UCEC	SNRPGP7 →	+0.283	+4.335	<.001	.007	3	2
UCEC	RNU6-719P →	+0.308	+4.582	.004	.005	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
UCEC	IGKV1OR-2 →	+0.315	+3.393	.001	.007	3	1
BRCA	WBP1LP5 →	+0.093	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

RNU6-1227P by SNRPG expression — UCEC

Explore this box plot interactively →