Q-omics provides the consensus-scored RNU6-1227P profile across patient tissues and cancer cell-line models. RNU6-1227P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, RNU6-1227P RNA expression shows 4,693 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight LUSC as cancer lineages where RNU6-1227P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-1227P survival associations across molecular data types. RNU6-1227P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-1227P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	LUSC (144)	view →

This table ranks reproducible RNU6-1227P RNA expression–survival associations across cancer types. High RNU6-1227P expression shows unfavorable associations in LUSC, HNSC, MESO, ACC and ESCA, but favorable associations in BLCA. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUSC as the clearest survival context for RNU6-1227P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.243	0.764	<.001	144	view →
HNSC	OS	Tertile	II,III,IV	0.075	0.756	<.001	108	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
BLCA	DFS	Tertile	II,III,IV	0.872	0.609	.026	45	view →
ESCA	OS	Tertile	II,III,IV	0.382	0.710	.032	18	view →

Pink = unfavorable, green = favorable. all 12 lineages →

RNU6-1227P-LUSC (OS)

Kaplan–Meier survival curve for RNU6-1227P RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-1227P in patient tissues and cancer cell lines. In patient samples, RNU6-1227P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,693	LUSC (915)	view →
Function (RNA)	3,399	STAD (1915)	view →