SNRPG

Across TCGA pan-cancer cohorts, SNRPG RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of SNRPG’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SNRPG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNRPG is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, BLCA, and KIRC are the cancer types where SNRPG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRPG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+1.364	<.001	12	view →
BLCA	Male	III,IV	+1.045	<.001	11	view →
KIRC	All	All	+0.210	<.001	10	view →
LIHC	Male	II,III,IV	+1.045	<.001	9	view →
STAD	Female	All	+1.277	<.001	8	view →
COAD	Female	II,III,IV	+1.048	<.001	8	view →
LUAD	Male	All	+0.831	<.001	8	view →
KICH	Female	II,III,IV	−1.634	<.001	7	view →
LUSC	Female	All	+1.204	<.001	7	view →
UCEC	All	All	+0.937	<.001	6	view →
BRCA	All	III,IV	+0.794	<.001	6	view →
ESCA	All	All	+1.561	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

SNRPG–HNSC

Open the HNSC breakdown →