SNRK

Across TCGA patient cohorts, SNRK mutation is significantly associated with the RNA expression of many other genes, with 4,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRK-associated genes across cancer lineages are RN7SL134P, NF1P10, and RN7SL248P. Each is linked with SNRK in more than 3 cancer types. Because this analysis shows association rather than direction, both SNRK-to-partner and partner-to-SNRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by SNRK-low versus SNRK-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRK→partner) and Y-score (partner→SNRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.075	+1.645	.003	.005	3	4
CESC	NF1P10 →	+0.390	+7.154	<.001	<.001	3	3
SKCM	RN7SL248P →	+0.030	+4.025	<.001	.007	3	3
SKCM	RNU6-718P →	+0.306	+2.502	.002	.005	3	2
UCEC	MIR6803 →	+0.100	+3.893	<.001	<.001	3	2
UCEC	LIN7C →	+0.532	+2.214	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,899 associations by consensus.

RN7SL134P by SNRK expression — UCEC

Explore this box plot interactively →