SNRK

Across TCGA pan-cancer cohorts, SNRK RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SNRK’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SNRK RNA is repressed in tumor relative to normal tissue. In most cancer types SNRK is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and BLCA are the cancer types where SNRK tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRK RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−1.634	<.001	9	view →
LUSC	Female	II,III,IV	−1.484	<.001	9	view →
BLCA	All	All	−0.635	<.001	8	view →
THCA	All	All	−0.474	<.001	8	view →
KICH	Male	All	−1.323	<.001	7	view →
COAD	Female	All	−0.838	<.001	7	view →
KIRP	Male	All	−0.733	<.001	6	view →
BRCA	All	All	−0.556	<.001	6	view →
UCEC	All	All	−1.060	<.001	4	view →
READ	Female	All	−1.050	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SNRK–LUAD

Open the LUAD breakdown →