SNRK

Across TCGA cell cohorts, SNRK mutation is significantly associated with the RNA expression of many other genes, with 278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNRK-associated genes across cancer lineages are OR2J3, GALR3, and S100G. Each is linked with SNRK in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRK-to-partner and partner-to-SNRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J3 grouped by SNRK-low versus SNRK-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRK→partner) and Y-score (partner→SNRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2J3 →	+0.019	+3.938	.001	.005	3	2
LARGE_INTESTINE	GALR3 →	+0.115	+3.839	<.001	<.001	3	2
LARGE_INTESTINE	S100G →	+0.746	+2.425	.003	.004	3	2
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	2
URINARY_TRACT	TARM1 →	+0.026	+5.087	<.001	.004	3	1
OVARY	OR2M4 →	+0.055	+3.700	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

OR2J3 by SNRK expression — OVARY

Explore this box plot interactively →