SNPH

Across TCGA patient cohorts, SNPH protein abundance is significantly associated with the RNA expression of many other genes, with 4,569 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNPH-associated genes across cancer lineages are CGRRF1, RNA5SP161, and RNU7-119P. Each is linked with SNPH in more than 2 cancer types. Because this analysis shows association rather than direction, both SNPH-to-partner and partner-to-SNPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNPH versus CGRRF1 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNPH→partner) and Y-score (partner→SNPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CGRRF1 →	+0.759	+0.954	<.001	.001	3	3
UCEC	RNA5SP161 →	+1.653	+1.443	.009	.005	3	2
UCEC	RNU7-119P →	+2.670	+0.996	<.001	.006	3	2
GBM	MRO →	+0.814	+0.416	.003	.003	3	2
LUAD	RBM17 →	+0.298	+0.981	.007	.001	3	2
LUAD	RPRD1A →	+0.559	+0.822	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,569 associations by consensus.

SNPH vs CGRRF1 — BRCA

Explore this scatter interactively →