Across TCGA patient cohorts, SNORD74B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,123 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNORD74B-associated proteins across cancer lineages are MTHFD2, ARHGEF17, and ZCCHC24. Each is linked with SNORD74B in more than 3 cancer types. Because this analysis shows association rather than direction, both SNORD74B-to-partner and partner-to-SNORD74B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD74B→partner) and Y-score (partner→SNORD74B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTHFD2 →	-0.644	-1.235	<.001	<.001	3	4
CCRCC	ARHGEF17 →	+0.378	+1.001	.001	.004	3	4
UCEC	ZCCHC24 →	+0.555	+1.682	<.001	<.001	3	4
PDAC	RFC1_S368 →	-0.776	-1.117	<.001	<.001	3	4
OV	SYNPO2_S155 →	+1.877	+0.405	<.001	.005	3	4
UCEC	TNS2_S102 →	+0.613	+1.104	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,123 associations by consensus.

Exploration

SNORD74B survival (RNA) · tumor vs normal (RNA) · all SNORD74B data types