SNORD116-4

Across TCGA patient cohorts, SNORD116-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,160 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SNORD116-4-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Regulation of microtubule cytoskeleton organization, and Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with SNORD116-4 in more than 31 cancer types. Because this analysis shows association rather than direction, both SNORD116-4-to-partner and partner-to-SNORD116-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by SNORD116-4-low versus SNORD116-4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-4→partner) and Y-score (partner→SNORD116-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.078	+1.537	<.001	<.001	3	32
UCS	Regulation of microtubule cytoskeleton organization →	+0.045	+1.857	<.001	.001	3	32
DLBC	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.073	+1.483	<.001	<.001	3	32
DLBC	Transcription initiation-coupled chromatin remodeling →	+0.073	+0.950	.001	.001	3	32
DLBC	Golgi organization →	+0.059	+1.232	<.001	<.001	3	32
DLBC	Protein desumoylation →	+0.096	+1.189	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,160 associations by consensus.

Nuclear-transcribed mRNA catabolic process by SNORD116-4 expression — DLBC

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