SNORD116-4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD116-4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD116-4-associated genes across cancer lineages are Eosinophils and Platelets. Each is linked with SNORD116-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-4-to-partner and partner-to-SNORD116-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by SNORD116-4-low versus SNORD116-4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-4→partner) and Y-score (partner→SNORD116-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMEosinophils →+0.091+3.708<.001.00431
LUSCPlatelets →+0.017+3.727.029.04631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Eosinophils by SNORD116-4 expression — SKCM

Box plot of Eosinophils in SNORD116-4-low vs SNORD116-4-high samples in SKCM.

Explore this box plot interactively →

Exploration