SNORD116-27

Across TCGA patient cohorts, SNORD116-27 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,022 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SNORD116-27-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, Protein localization to chromosome, telomeric region, and Positive regulation of mRNA processing. Each is linked with SNORD116-27 in more than 25 cancer types. Because this analysis shows association rather than direction, both SNORD116-27-to-partner and partner-to-SNORD116-27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by SNORD116-27-low versus SNORD116-27-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-27→partner) and Y-score (partner→SNORD116-27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cytoskeleton-dependent intracellular transport →	+0.062	+0.353	<.001	<.001	3	26
ESCA	Protein localization to chromosome, telomeric region →	+0.090	+0.261	<.001	<.001	3	25
ESCA	Positive regulation of mRNA processing →	+0.104	+0.289	<.001	<.001	3	24
ESCA	Histone mRNA metabolic process →	+0.078	+0.285	<.001	<.001	3	24
ESCA	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.093	+0.399	<.001	<.001	3	24
ESCA	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.085	+0.189	<.001	.002	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,022 associations by consensus.

Cytoskeleton-dependent intracellular transport by SNORD116-27 expression — ESCA

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