SNORD116-27

Across TCGA patient cohorts, SNORD116-27 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-27-associated genes across cancer lineages are RPS29P26, RNU6-365P, and MIR4427. Each is linked with SNORD116-27 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-27-to-partner and partner-to-SNORD116-27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P26 grouped by SNORD116-27-low versus SNORD116-27-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-27→partner) and Y-score (partner→SNORD116-27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPS29P26 →	+0.266	+7.816	<.001	.008	3	1
SKCM	RNU6-365P →	+0.843	+7.816	<.001	.008	3	1
SKCM	MIR4427 →	+0.553	+7.816	<.001	.008	3	1
SKCM	RNF138P2 →	+0.049	+7.816	<.001	.008	3	1
STAD	RNA5SP514 →	+0.162	+4.641	<.001	.005	3	1
STAD	FTLP4 →	+0.183	+3.878	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

RPS29P26 by SNORD116-27 expression — SKCM

Explore this box plot interactively →