SNORD116-23

Across TCGA patient cohorts, SNORD116-23 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,588 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-23-associated GO terms across cancer lineages are Macromolecule methylation, Translational elongation, and Nuclear-transcribed mRNA catabolic process. Each is linked with SNORD116-23 in more than 18 cancer types. Because this analysis shows association rather than direction, both SNORD116-23-to-partner and partner-to-SNORD116-23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by SNORD116-23-low versus SNORD116-23-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-23→partner) and Y-score (partner→SNORD116-23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Macromolecule methylation →	+0.079	+0.231	<.001	.002	3	19
THYM	Translational elongation →	+0.052	+0.156	.004	.003	3	18
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.097	+0.271	<.001	<.001	2	19
ESCA	Regulation of RNA splicing →	+0.096	+0.181	<.001	.004	2	19
ESCA	Transport along microtubule →	+0.067	+0.190	<.001	.003	3	17
ESCA	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.098	+0.241	<.001	.005	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,588 associations by consensus.

Macromolecule methylation by SNORD116-23 expression — ESCA

Explore this box plot interactively →