Across TCGA patient cohorts, SNORD116-19 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD116-19-associated genes across cancer lineages are MIR6729, MTCO2P21, and SULT1D1P. Each is linked with SNORD116-19 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-19-to-partner and partner-to-SNORD116-19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-19→partner) and Y-score (partner→SNORD116-19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6729 →	+0.662	+6.469	<.001	.001	3	1
SKCM	MTCO2P21 →	+0.108	+5.970	<.001	.002	3	1
SKCM	SULT1D1P →	+0.054	+4.979	<.001	.009	3	1
SKCM	RPS23P4 →	+0.284	+4.979	<.001	.009	3	1
SKCM	COX6B1P2 →	+0.332	+5.292	<.001	.006	3	1
SKCM	ACTR3P3 →	+0.063	+5.594	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

SNORD116-19 survival (RNA) · tumor vs normal (RNA) · all SNORD116-19 data types