Across TCGA patient cohorts, SNORD116-18 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD116-18-associated genes across cancer lineages are OFD1P11Y, IGHD5-5, and MIR1298. Each is linked with SNORD116-18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-18-to-partner and partner-to-SNORD116-18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-18→partner) and Y-score (partner→SNORD116-18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
UCEC	IGHD5-5 →	+1.131	+8.066	<.001	.007	3	1
UCEC	MIR1298 →	+0.373	+8.066	<.001	.007	3	1
SKCM	OR51L1 →	+0.044	+7.816	<.001	.008	3	1
SKCM	RNU6-978P →	+0.548	+7.816	<.001	.008	3	1
SKCM	RNU6-281P →	+0.373	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

SNORD116-18 survival (RNA) · tumor vs normal (RNA) · all SNORD116-18 data types