Q-omics provides the consensus-scored RNU6-281P profile across patient tissues and cancer cell-line models. RNU6-281P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, RNU6-281P RNA expression shows 7,673 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight BRCA, and LUSC as cancer lineages where RNU6-281P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-281P survival associations across molecular data types. RNU6-281P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-281P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	BRCA (108)	view →

This table ranks reproducible RNU6-281P RNA expression–survival associations across cancer types. High RNU6-281P expression shows unfavorable associations in BRCA, UCEC, HNSC, THCA, LIHC and KIRC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for RNU6-281P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.553	0.925	<.001	108	view →
UCEC	OS	Tertile	II,III,IV	0.198	0.768	.002	72	view →
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	72	view →
THCA	DFS	Tertile	All	0.049	0.828	<.001	54	view →
LIHC	OS	Tertile	All	0.128	0.704	.011	36	view →
KIRC	DFS	Tertile	IV	0.114	0.626	<.001	36	view →

Pink = unfavorable, green = favorable. all 7 lineages →

RNU6-281P-BRCA (OS)

Kaplan–Meier survival curve for RNU6-281P RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-281P in patient tissues and cancer cell lines. In patient samples, RNU6-281P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,673	LUSC (4307)	view →
Function (RNA)	4,741	STAD (4591)	view →