Across TCGA patient cohorts, SNORD115-4 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNORD115-4-associated genes across cancer lineages are RN7SL105P, MIR7702, and MIR203A. Each is linked with SNORD115-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-4-to-partner and partner-to-SNORD115-4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-4→partner) and Y-score (partner→SNORD115-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL105P →	+0.094	+3.449	.004	.009	3	1
UCEC	MIR7702 →	+0.949	+7.060	<.001	<.001	3	1
LUAD	MIR203A →	+0.735	+4.722	<.001	.003	3	1
LUAD	FTLP4 →	+0.104	+4.712	<.001	.007	3	1
LUAD	SLC25A20P1 →	+0.049	+4.984	<.001	.005	3	1
LUAD	RPL21P91 →	+0.125	+4.453	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

SNORD115-4 survival (RNA) · tumor vs normal (RNA) · all SNORD115-4 data types