Across TCGA pan-cancer cohorts, SNORD115-4 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SNORD115-4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SNORD115-4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD115-4 is over-expressed in tumor.

BRCA are the cancer types where SNORD115-4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD115-4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.107	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SNORD115-4 RNA expression & survival · all SNORD115-4 data types