Across TCGA patient cohorts, SNORD115-37 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-37-associated genes across cancer lineages are CYCSP53, RPS23P4, and RN7SL50P. Each is linked with SNORD115-37 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-37-to-partner and partner-to-SNORD115-37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-37→partner) and Y-score (partner→SNORD115-37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CYCSP53 →	+0.329	+5.771	<.001	.003	3	1
SKCM	RPS23P4 →	+0.140	+4.979	<.001	.009	3	1
SKCM	RN7SL50P →	+0.200	+5.680	<.001	.003	3	1
SKCM	OR5W2 →	+0.068	+5.292	<.001	.006	3	1
SKCM	CEACAMP7 →	+0.407	+5.680	<.001	.003	3	1
SKCM	LINC00382 →	+0.107	+5.097	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

SNORD115-37 survival (RNA) · tumor vs normal (RNA) · all SNORD115-37 data types