Across TCGA patient cohorts, SNORD115-34 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD115-34-associated genes across cancer lineages are RIMBP3B, RNU1-68P, and TRBV11-3. Each is linked with SNORD115-34 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-34-to-partner and partner-to-SNORD115-34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-34→partner) and Y-score (partner→SNORD115-34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RIMBP3B →	+0.040	+3.833	<.001	.005	3	1
UCEC	RNU1-68P →	+0.171	+4.877	<.001	.003	3	1
UCEC	TRBV11-3 →	+0.439	+3.756	.002	.006	3	1
SKCM	ACTR6P1 →	+0.044	+7.816	<.001	.008	3	1
LUAD	ELOAP1 →	+0.031	+5.888	<.001	.002	3	1
LUAD	TOMM22P4 →	+0.172	+8.342	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

SNORD115-34 survival (RNA) · tumor vs normal (RNA) · all SNORD115-34 data types