Across TCGA pan-cancer cohorts, SNORD115-34 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated SNORD115-34 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SNORD115-34 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-34 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

KIRP, STAD, and LGG are the cancer types where SNORD115-34 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.199	0.885	<.001	45	view →
STAD	DFS	Tertile	All	0.398	0.661	.019	18	view →
LGG	DFS	Tertile	All	1.000	0.826	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORD115-34 tumor-vs-normal RNA expression · all SNORD115-34 data types