Across TCGA patient cohorts, SNORD115-30 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-30-associated genes across cancer lineages are RN7SL291P, OR7G15P, and ELMO2P1. Each is linked with SNORD115-30 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-30-to-partner and partner-to-SNORD115-30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-30→partner) and Y-score (partner→SNORD115-30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL291P →	+0.145	+6.327	<.001	<.001	3	2
SKCM	OR7G15P →	+0.098	+3.495	<.001	.001	3	1
SKCM	ELMO2P1 →	+0.076	+2.609	<.001	.009	3	1
SKCM	RN7SL607P →	+0.192	+3.127	<.001	.003	3	1
SKCM	KCNIP4-IT1 →	+0.008	+3.603	<.001	<.001	3	1
SKCM	FAM96AP1 →	+0.052	+3.990	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

Exploration

SNORD115-30 survival (RNA) · tumor vs normal (RNA) · all SNORD115-30 data types