Across TCGA patient cohorts, SNORD115-23 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-23-associated genes across cancer lineages are MTATP6P20, RNU7-194P, and RN7SL310P. Each is linked with SNORD115-23 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-23-to-partner and partner-to-SNORD115-23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-23→partner) and Y-score (partner→SNORD115-23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTATP6P20 →	+0.085	+4.513	<.001	.009	3	1
SKCM	RNU7-194P →	+0.666	+6.665	<.001	<.001	3	1
SKCM	RN7SL310P →	+0.210	+5.080	<.001	.004	3	1
SKCM	RPL39P31 →	+0.190	+4.680	<.001	.007	3	1
SKCM	NDUFA5P5 →	+0.101	+4.594	<.001	.008	3	1
SKCM	RN7SL814P →	+0.154	+4.970	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

SNORD115-23 survival (RNA) · tumor vs normal (RNA) · all SNORD115-23 data types