Across TCGA pan-cancer cohorts, SNORD115-23 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated SNORD115-23 data layer compared with 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNORD115-23 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-23 expression acts as an unfavorable survival marker.

UCEC and BLCA are the cancer types where SNORD115-23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.121	0.679	.005	54	view →
BLCA	DFS	Tertile	III,IV	0.218	0.574	.041	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORD115-23 tumor-vs-normal RNA expression · all SNORD115-23 data types