SNORD115-2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-2 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-2-associated genes across cancer lineages are PCYT1B-AS1, SOCS2P1, and RNU6-587P. Each is linked with SNORD115-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-2-to-partner and partner-to-SNORD115-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-2→partner) and Y-score (partner→SNORD115-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPCYT1B-AS1 →+0.158+5.655<.001.00432
SKCMSOCS2P1 →+0.064+4.039<.001.00932
LUADRNU6-587P →+0.292+7.930<.001.00832
LUSCRNA5SP176 →+0.351+7.924<.001.00832
SKCMRNU4-58P →+0.228+4.233<.001.00132
SKCMLATS2-AS1 →+0.128+3.448<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

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