SNORD115-19

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-19 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-19-associated genes across cancer lineages are SAP18P1, RAC1P7, and OR2AM1P. Each is linked with SNORD115-19 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-19-to-partner and partner-to-SNORD115-19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-19→partner) and Y-score (partner→SNORD115-19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSAP18P1 →+0.087+4.328<.001.00732
SKCMRAC1P7 →+0.083+4.624<.001.00531
SKCMOR2AM1P →+0.158+4.469<.001.00631
SKCMRN7SL259P →+0.153+3.766<.001.00531
SKCMLINC02213 →+0.033+4.199<.001.00931
SKCMPHBP6 →+0.032+4.993<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

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